Wall Ventilation
If the room where you want the portable A/c to work has an exterior wall, you can vent the exhaust through the wall. All you have to do is cut a correct size hole with a jigsaw in the wall. However, do not end up digging the hole in a wall where there is plumbing work done or electrical wiring is there. Once you insert a hose through the hole, seal the edges of the hole with silicone caulk.
Connecting to Dryer Vents
Many people use dryer vents to exhaust the heat from the portable air conditioners. The manufacturers of portable A/cs do not recommend it. This is because the diameter of the vent hose is greater than the diameter of the dryer vent. The standard diameter of a standard dryer vent is 4″. The diameter of hoses of portable air conditioner is 5″ on an average. Some units have smaller diameter vent hoses, and these units may be vented out a dryer vent. If you have a flap at the end of the vent, then do not use it. The compressor of the portable a/c is not strong enough to push these flaps open. If you need to cover that exterior opening of the vent, cover it with a screen.